We are a translational research group that focuses on the improvement of diagnostics, early detection of treatment resistance and identification of novel molecular therapies to eventually contribute to advance personalized medicine. As part of the DKTK, we access the research power and clinical expertise of 20 institutions and teaching hospitals at 8 different locations in Germany to facilitate the transfer of basic cancer research to clinical applications. Our three main research topics are liquid biopsy, preclinical cancer models and next generation sequencing-based cancer profiling studies.