DKTK/CCCC-Seminar: High-throughput functional cancer genomics in mice

Veranstaltung ausschließlich für Fachpublikum

German Cancer Consortium (DKTK)

Dear Colleagues,
We cordially invite you to the next DKTK / CCCC Seminar. Our guest will be Univ.-Prof. Dr. med. Roland Rad (Klinikum rechts der Isar, Technische Universität München) presenting his work on high-throughput functional cancer genomics in mice.
 
Speaker: Univ.-Prof. Dr. med. Roland Rad
Title: High-throughput functional cancer genomics in mice
Date: Monday, March 23, 2015, 4:30 pm
Venue: Charité, Comprehensive Cancer Center | Conference room, 3rd Floor
   
Roland Rad, a clinician scientist at the DKTK partner site Klinikum rechts der Isar, Technische Universität München, has developed novel transposon-based tool kits for insertional mutagenesis in mice to uncover genetic networks of tumorigenesis in a forward genetic approach. He will show, how these tools enable the study of biological processes, such as tumor initiation, progression, metastasis or treatment resistance on a genome-wide scale at an organismal level.
 
Please see the attached flyer announcement for the upcoming DKTK/CCCC Seminar.
 
A genetic progression model of Braf(V600E)-induced intestinal tumorigenesis reveals targets for therapeutic intervention. Rad R, Cadiñanos J, Rad L, Varela I, Strong A, Kriegl L, Constantino-Casas F, Eser S, Hieber M, Seidler B, Price S, Fraga MF, Calvanese V, Hoffman G, Ponstingl H, Schneider G, Yusa K, Grove C, Schmid RM, Wang W, Vassiliou G, Kirchner T, McDermott U, Liu P, Saur D, Bradley A. Cancer Cell. 2013 Jul 8;24(1):15-29. doi: 10.1016/j.ccr.2013.05.014. PMID: 23845441
 
A conditional piggyBac transposition system for genetic screening in mice identifies oncogenic networks in pancreatic cancer. Rad R, Rad L, Wang W, Strong A, Ponstingl H, Bronner IF, Mayho M, Steiger K, Weber J, Hieber M, Veltkamp C, Eser S, Geumann U, Öllinger R, Zukowska M, Barenboim M, Maresch R, Cadiñanos J, Friedrich M, Varela I, Constantino-Casas F, Sarver A, Ten Hoeve J, Prosser H, Seidler B, Bauer J, Heikenwälder M, Metzakopian E, Krug A, Ehmer U, Schneider G, Knösel T, Rümmele P, Aust D, Grützmann R, Pilarsky C, Ning Z, Wessels L, Schmid RM, Quail MA, Vassiliou G, Esposito I, Liu P, Saur D, Bradley A. Nat Genet. 2015 Jan;47(1):47-56. doi: 10.1038/ng.3164. Epub 2014 Dec 8. PMID: 25485836
 
We are looking forward to welcoming you at the talk.
All are most warmly invited to attend! Please feel free to circulate this invitation.
 
Best regards,
 
Doreen Ditzen

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